Mutation Datasets

Released Date: February 27, 2025

Mutation Dataset

We have annotated genetic variants from ClinVar, UK Biobank, and gnomAD using ProteinIS to determine whether amino acid changes occur at protein-protein interaction (PPI) sites. Explore these annotations through our interactive query interface or download complete datasets from the Download section.

ID Chromosome Position Uploaded Variation Reference Allele Alternate Allele Clinical Review Status Clinical Significance Consequence Existing Variation SWISSPROT TREMBL Protein Position Amino Acids Canonical SIFT Type SIFT Score Polyphen Type Polyphen Score PPI 3Dmapper Result Gene Feature Gene Symbol